Dr. Birgit Liliensiek: Scientific Publications

Original Publications:

17. Andrassy M, Igwe J, Autschbach F, Volz C, Remppis A, Neurath MF, Schleicher E, Humpert PM, Wendt T,

Liliensiek B, Morcos M, Schiekofer S, Thiele K, Chen J, Kientsch-Engel R, Schmidt AM, Stremmel W, Stern DM, Katus HA, Nawroth PP, Bierhaus A. 1223-37. Posttranslationally modified proteins as mediators of sustained intestinal inflammation.

Am J Pathol. 2006 Oct;169(4):1223-37.

 

16. Kurschus FC, Oelert T, Liliensiek B, Buchmann P, Wraith DC, Hämmerling GJ, Arnold B. Experimental autoimmune encephalomyelitis in mice expressing the autoantigen MBP 1-10 covalently bound to the MHC class II molecule I-Au.

Int Immunol. 2006 Jan;18(1):151-62.

 

15. Bierhaus A, Haslbeck KM, Humpert PM, Liliensiek B, Dehmer T, Morcos M, Sayed AA, Andrassy M, Schiekofer S, Schneider JG, Schulz JB, Heuss D, Neundörfer B, Dierl S, Huber J, Tritschler H, Schmidt AM, Schwaninger M, Haering HU, Schleicher E, Kasper M, Stern DM, Arnold B, Nawroth PP. Loss of pain perception in diabetes is dependent on a receptor of the immunoglobulin superfamily.

J Clin Invest. 2004 Dec;114(12):1741-51.

 

14. Liliensiek B, Weigand MA, Bierhaus A, Nicklas W, Kasper M, Hofer S, Plachky J, Gröne HJ, Kurschus FC, Schmidt AM, Yan SD, Martin E, Schleicher E, Stern DM, Hämmerling G Gü, Nawroth PP, Arnold B. Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response.

J Clin Invest. 2004 Jun;113(11):1641-50.

 

13. Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, Armstrong DL, Arnold B, Liliensiek B, Nawroth P, Hofman F, Kindy M, Stern D, Zlokovic B. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier

and accumulation in brain.

Nat Med. 2003 Jul;9(7):907-13.

 

12. Sakaguchi T, Yan SF, Yan SD, Belov D, Rong LL, Sousa M, Andrassy M, Marso SP, Duda S, Arnold B, Liliensiek B, Nawroth PP, Stern DM, Schmidt AM, Naka Y. Central role of RAGE-dependent neointimal expansion in arterial restenosis. 

J Clin Invest. 2003 Apr;111(7):959-72.

 

11. Wendt TM, Tanji N, Guo J, Kislinger TR, Qu W, Lu Y, Bucciarelli LG, Rong LL, Moser B, 

Markowitz GS, Stein G, Bierhaus A, Liliensiek B, Arnold B, Nawroth PP, Stern DM, D'Agati VD, Schmidt AM. RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy.

Am J Pathol. 2003 Apr;162(4):1123-37.

10. Constien R, Forde A, Liliensiek B, Gröne H-J, Nawroth P, Hämmerling G, Arnold B (2001).

Characterization of a novel EGFP reporter mouse to monitor cre recombination as demonstrated by a tie2 cre mouse line.

Genesis 30: 36-44.

 

9. Bierhaus A, Chen J, Liliensiek B, Nawroth PP (2000). LPS and cytokine activated

 endothelium. Seminars in 

Thrombosis and Hemostasis 26 (5): 571-587.

 

8. Greten J, Kreis I, Liliensiek B, Allenberg J, Amiral J, Ziegler R, Nawroth PP (1998)

Localisation of protein Z in vascular lesions of patients with atherosclerosis.

VASA 27: 144-148.

 

7. Liliensiek B, Rocha M, Umansky V, Benner A, Lin J, Ziegler R, Nawroth PP, Schirrmacher V (1998)

Identification of four genes in endothelial cells whose expression is affected by tumor cells and host immune status- A study in ex vivo isolated endothelial cells.

Blood 92 (9): 3394-3404.

 

6. Liliensiek B. (1997)

Untersuchung der biologischen Relevanz TNF- supprimierter, endothelialer Gene nach verschiedenen Stimuli in vitro und unter pathophysiologischen Bedingungen in vivo. Doktorarbeit, Medizinische Fakultät der Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany.

 

5. Lin J, Liliensiek B, Kanitz M, Schimanski U, Ziegler R, Kauffmann G, Nawroth PP (1998)

Molecular cloning of genes differentially regulated by TNF-alpha in bovine aortic endothelial cells, fibroblasts and smooth muscle cells.

Cardiovascular Res 38: 802-813.

 

4. Zhang Y, Deng Y, Wendt T, Liliensiek B, Bierhaus A, Greten J, He W, Chen B, Hach-Wunderle V, Waldherr R, Ziegler R, Männel D, Stern DM, Nawroth PP (1996)

Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor-induced tissue factor expression and fibrin deposition in mouse Meth-A sarcomas.

J Clin Invest 97: 2213-2224.

 

3. Hemmer CJ, Bierhaus A, v Riedesel J, Gabat S, Liliensiek B, Pitronik P, Lin J, Grauer A, Amiral J, Ziegler R, Schieffer S, Kern P, Seitz R, Egbring R, Dietrich M, Nawroth PP (1994)

Elevated thrombomodulin plasma levels as a result of endothelial involvement in Falciparum Malaria.

Thromb Haemost 72: 457-464.

 

2. Schwermann B, Pfau K, Liliensiek B, Schleyer M, Fischer T, Bakker EP (1994)

Purification, properties and structural aspects of a thermoacidophilic alpha-amylase from Alicyclobacillus acidocaldarius atcc 27009. Insight into acidostability of proteins.

Eur J Biochem 226: 981-991.

 

1. Liliensiek B (1992)

Molekularbiologische Untersuchungen an Bacillus acidocaldarius-Genen.

Diplomarbeit, Universität Osnabrück, Niedersachsen, Germany.

 

 

book chapters and reviews:

 

3. Liliensiek B, Sido B, Nawroth PP (1999)

Grundlagen der Endothelzellaktivierung bei der Transplantatabstoßung. In: Nawroth PP, Lasch HG (Hrsg): Lehrbuch der Inneren Medizin. 1. Aufl. Uni.Med, Lorch-Württemberg, in print.

 

2. Nawroth PP, Zhang Y, Lin J, Liliensiek B, Bierhaus A, v. Riedesel J, Deng J, Ziegler R (1994)

Mechanismus der Endothelzellaktivierung, 21-25. In: Heidbreder E, Götz R, Heidland A (Hrsg): Nierentransplantation. 1. Aufl. Beck.

 

1. Nawroth PP, Lu J, Abel M, Zhang Y, FzE Riedesel J, Bierhaus A, Liliensiek B, Vettermann O, Lin J, Kasperk HC, Ziegler R (1993)

Endothelzellstimulation durch AGE`s - Ein In-Vitro-Modell diabetischer Spätschäden, 33-41. In: Hasslacher C, Spanuth E (Hrsg): Diabetes und Angiopathie. 1. Aufl. Springer, Heidelberg